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Hi, i have a pre-installed win 8, Dell inspiron 3421, secure boot on I had the same problem and based on some of the answer's above, did the following

1) Reboot 2) Press F12 before grub loads 3) go to Change Boot Mode Setting 4) once there you'll see 2 options, select UEFI Boot Mode, Secure Boot Off.

and that's it

it worked 4 me, i switched on and off to see if that was the problem , and now VirtualBox loads with no error hope this help.