Some of the system-config have a replacement in the Gnome settings, for example time-zone configuration or user and group maintenance. For others, the cockpit package could be a valid replacement.
Some of the system-config programs depend on python2.7, and as python2.7 is about to be retired, the system-config programs either needs to be converted to python3 or they will disappear. system-config-date, for example, is already dead.